Dissolution and In-Vitro Release Testing

Dissolution and In-Vitro Release Testing contains 3 topic pages in Pharmaceutical Quality Assurance.

Dissolution testing measures the rate and extent to which an active pharmaceutical ingredient is released from a solid oral dosage form into solution under standardised experimental conditions, and serves as a critical quality control tool and a surrogate predictor of in vivo drug absorption. This chapter examines the compendial dissolution apparatus, the principles governing dissolution method development, the biopharmaceutics classification system, and the concept of in vitro-in vivo correlation.