2.3.2 Ion Channels

Ion channels may be ligand-gated (for example GABA-A or nicotinic acetylcholine receptors) or voltage-gated (sodium, potassium, or calcium...

Ion channels may be ligand-gated (for example GABA-A or nicotinic acetylcholine receptors) or voltage-gated (sodium, potassium, or calcium channels). Drugs modulating ion channels underlie anaesthetics, antiepileptics, and antiarrhythmics, acting by altering channel open probability, conductance, or gating kinetics.