4.5 Route of Administration and Dose Calculation
4.5 Route of Administration and Dose Calculation contains 2 topic pages in Phase 4 — In-Vivo Animal Studies & Study Design.
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4.5.1 Routes of Administration
The oral (per os) route, administered by gavage using a graduated feeding needle, permits a maximum volume of approximately 10 mL/kg in the rat; correct...
4.5.2 Human-to-Animal Dose Conversion
Because metabolic rate does not scale linearly with body weight, a simple per-kilogram conversion of a human dose to an animal dose is scientifically...